# modificationOfTwoSubstratesI -- an example chemical reaction motif

## Description

In this system, two cycles are connected through a joint catalyzing kinase and a joint catalyzing phosphotase [Feliu, Wiuf].

 i1 : modificationOfTwoSubstratesI() o1 = S_0+E-->X_1 X_1-->S_0+E X_1-->E+S_1 S_1+F-->Y_1 Y_1-->S_1+F Y_1-->S_0+F E+P_0-->X_2 X_2-->E+P_0 X_2-->E+P_1 F+P_1-->Y_2 Y_2-->F+P_1 Y_2-->F+P_0 o1 : ReactionNetwork

In the motif Modification of Two Different Substrates I, the symbols used in the chemical reactions have the following meaning:

S_i and P_i are substrates with i = 0, 1, 2 phosphorylated sites, E is a kinase and F is a phosphotase, X and Y are the intermediate complexes formed by the enzymes E and F, respectively.

To rename species, use substitute(ReactionNetwork,List).

## Ways to use modificationOfTwoSubstratesI :

• "modificationOfTwoSubstratesI()"

## For the programmer

The object modificationOfTwoSubstratesI is .